The major (such as Computer Science or Biological Sciences) is exactly the same regardless of which college you attend: the major requirements, professors, classes, rigor, and research opportunities are all the same. The difference is in the requirements outside of the major as each college has different distribution requirements. You’ll want to think about what other classes you want to take beyond the major and visit the websites for the College of Arts & Sciences and the other college that you are considering, to see which would be the best fit. If you are thinking about double majoring, keep in mind that you can only select another major from within the same college.